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cello - Genetic circuit design automation

  •    Java

The Cello input is a high-level logic specification written in Verilog, a hardware description language. The code is parsed to generate a truth table, and logic synthesis produces a circuit diagram with the genetically available gate types to implement the truth table. The gates in the circuit are assigned using experimentally characterized genetic gates. In assignment, a predicted circuit score guides a breadth-first search, or a Monte Carlo simulated annealing search. The assignment with the highest score is chosen, and this assignment can be physically implemented in a combinatorial number of different genetic layouts. The Eugene language is used for rule-based constrained combinatorial design of one or more final DNA sequence(s) for the designed circuit. Verilog programs start with a module keyword, followed by the module name, followed by the list of output and input wire names. Within a module definition, Cello currently parses three forms of Verilog: case statements, assign statements, and structural elements (examples below). Verilog code can be entered using a text editor and saved with a .v extension.