Sambamba is a high performance highly parallel robust and fast tool (and library), written in the D programming language, for working with SAM and BAM files. Because of its efficiency is an important work horse running in many sequencing centres around the world today. Current functionality is an important subset of samtools functionality, including view, index, sort, markdup, and depth. Most tools support piping: just specify /dev/stdin or /dev/stdout as filenames. When we started writing sambamba (in 2012) the main advantage over samtools was parallelized BAM reading and writing. In March 2017 samtools 1.4 was released, reaching parity on this. A recent performance comparison shows that sambamba holds its ground and can do better in different configurations. Here are some comparison metrics. For example for flagstat sambamba is 1.4x faster than samtools. For index they are similar. For Markdup almost 6x faster and for view 4x faster. For sort sambamba has been beaten generally, though sambamba is up to 2x faster on large RAM machines.