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DDD is a graphical front-end for command-line debuggers such as GDB, DBX, WDB, Ladebug, JDB, XDB, the Perl debugger, the bash debugger, or the Python debugger. DDD displays data structures as graphs and plots.
NHibernate is a mature, open source object-relational mapper for the .NET framework. NHibernate is a port of Hibernate Core for Java to the .NET Framework. It handles persisting plain .NET objects to and from an underlying relational database.
Valgrind is an award-winning instrumentation framework for building dynamic analysis tools. There are Valgrind tools that can automatically detect many memory management and threading bugs, and profile your programs in detail. You can also use Valgrind to build new tools.
MIRA - Sequence assembler and mapper for whole genome shotgun and EST / RNASeq sequencing data. Can use Sanger, 454, Illumina and IonTorrent data. PacBio: CCS and ecCLR data usable, CLR not yet. Please visit http://sourceforge.net/apps/mediawiki/mira-assembler/
Python for .NET is a package that gives Python programmers nearly seamless integration with the .NET Common Language Runtime (CLR) and provides a powerful application scripting tool for .NET developers.
LuaEdit is an IDE/Text Editor/Debugger for the Lua language. Its interface looks like MS Visual Studio .Net? and includes syntax highlighting, code completion, advance breakpoint management, efficient search engines, etc. Client under GPL and server (core debugger) under LGPL.