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GPCompute is an old CUDA-like but Based on DX81 (or later) for compatibility with almost any current Videocards. It's Developped in C/C++. With Simple Interface for Arrayed-Computations. The Limitation all came from its DX version implemention.
PyGWA is library providing a set of tools for general purpose GPU computing. It is intended to be (relatively) easy to use and support various devices / frameworks but currently it supports AMD Stream SDK only and is heavily influenced by its 'streaming' philosophy. Other frameworks (hopefully) will be supported in the future.
Efficient implementation of Smith-Waterman algorithm in CUDA and OpenCL. So far I've released CUDA kernels but other parts (like command line tool to run the kernel and OpenCL kernel for ATI hardware) of the program will follow soon... ;) for GPU-GEMS kernels see Downloads