Dmbot - A bot that is on IRC and is a DM and is awesome.
Summary is informative enough I think.
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This IRC bot will administrate the card game quot;Love Letterquot; published by Alderac Entertainment. Configure it with your irc server, the channel you intend to play on, tell it who its administrators are, and choose your own name for the bot. Comes with a help file with bot commands.
Nested commands, easy configuration, and an incredibly flexible and easy-to-use plugin system distinguish Supybot from other IRC bots. There simply isn't a more flexible or easier to use IRC bot!
Windows (95/98/NT/2000/XP) ports of the Eggdrop IRC bot
Pidgin is an instant messaging program which lets you log in to accounts on multiple chat networks simultaneously. It runs on Windows, Linux, and other UNIX operating systems. Pidgin is compatible with the following chat networks out of the box: AIM, ICQ, Google Talk, Jabber/XMPP, MSN Messenger, Yahoo!, Bonjour, Gadu-Gadu, IRC, MXit, Novell GroupWise Messenger, Lotus Sametime, SILC, SIMPLE, MySpaceIM, and Zephyr.
Pandora is an artificial intelligent web based bot written in Java. Pandora is a component based AI architecture including, database memory, XML, voice, voice rec, chat, IRC, HTTP, Wiktionary, Freebase, consciousness, language, GUI, applet, web, jsp, Android
The IRC Bot Building Framework
RainbruRPG is a 3D multiplayer Role Playing Game project based on Ogre3D.
IRC defense bot, for all major IRC networks. Note that development and activity died in this project many years ago.
libIRC is a cross-platform framework for connecting to and interacting with Internet Relay Chat (IRC) networks. libIRC is useful as the foundation for embedding IRC capabilities into various applications such as chat clients, games, and irc bots.
Hubot is a chat bot, modeled after GitHub's Campfire bot. It is extendable with community scripts and your own custom scripts, and can work on many different chat services.