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amavisd-new is a high-performance interface between mailer (MTA) and content checkers amd virus scanners. It talks to MTA via (E)SMTP or LMTP or by using helper programs. It works best with Postfix, Sendmail and Exim v4, works with sendmail/milter, or with any MTA as a SMTP relay. The content received from the mail server is processed with Spam and Anti virus scanner and based on the results the mails will be quarantined.